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If you clear all three Strongholds in a region, that 300 Renown will cover most of the first two reward tiers for that region. Every Stronghold will, though, grant you 100 Renown. Not every Stronghold will become a marketplace or Waypoint, though.
![diablo 2 wiki act 1 diablo 2 wiki act 1](https://static.wikia.nocookie.net/diablo/images/4/4a/Chiltara.jpg)
Additionally, once the monsters are cleared out of certain Strongholds, the people will return - specifically healers and vendors like blacksmiths.
![diablo 2 wiki act 1 diablo 2 wiki act 1](https://www.purediablo.com/wp-content/uploads/2020/01/cropped-PD-Site-Logo-Sqaure-4-1.jpg)
There are four Acts in Diablo II, with an extra Act in Diablo II: Lord of Destruction.
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